MATH 680: Introduction to Computational Neuroscience

Instructor: Georgi Medvedev

Office hours: T 2:30-3:30 and by appointment

Office: 265 Korman Center

E-mail: medvedev@drexel.edu
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Syllabus

Here are a few examples of matlab codes for integrating Hodgkin-Huxley system:
hhkinetics.m: plots the graphs of the steady-state activation/inactivationfunctions and time constants as shown in Figure 2.13;
hhtraces.m: plots time series as in Figure 2.14;
hhrhs.m: defines the right hand side for the HH system;
hhinject.m: simulates experiment of injecting current into HH neuron.

Homework 1.

Homework 2.

Homework 3.

freqI.m: computes the frequency-current curve for the I_NaP+I_K model with high threshold I_K (type 1 model)
NaKmodel1.m: computes the frequency-current curve for the I_NaP+I_K model with low threshold I_K (type 2 model)

Lecture slides:
Two-dimensional systems.
Bursting.

Preprint on bursting .

Matlab resources online:

Student Presentations:
Minimal Models of Bursting Neurons.
Alternating and Synchronous Rhythms in Reciprocally Inhibitory Model Neurons.

MATLAB Primer by Kermit Sigmon