We propose a wavelet eigenvalue regression methodology for a high dimensional setting. Starting from the $p$-dimensional high-dimensional fractional signal-plus-noise model considered in the companion work (Abry, Boniece, Didier and Wendt (2021)), we propose a multiscale wavelet eigenvalue regression estimator
$$
\widehat{\ell}_{i} := \frac{1}{2}\Big(\sum_{j=j_1}^{j_2} w_j \log_2 \lambda_{i}\big({\mathbf W}(a(n)2^j)\big) -1\Big),\quad i=1,\ldots,p,
$$
for fixed octaves $j_1$, $j_2$ and regression weights $w_j$, where ${\mathbf W}(a(n)2^j)$ denotes the wavelet (sample covariance) random matrix at scale $a(n)2^j$, and $\lambda_i(\cdot)$ its $i^{th}$ eigenvalue in nondecreasing order. In a high-dimensional large-scale limit, we show that the fixed-dimensional subvector
$$
\{\widehat{h}_{q}\}_{q=1,\ldots,r} := \{ \widehat{\ell}_{i} \}_{i = p-r+1,\ldots,p}
$$
is a consistent and, under additional assumptions, asymptotically Gaussian estimator of the scaling eigenvalue structure $\{h_q\}_{q=1,\ldots,r}$ of the model, where $r$ denotes the effective dimension of the underlying process. We further construct a consistent estimator of the effective dimension $r$ that significantly increases the robustness of the methodology. The finite-sample performance of the proposed estimators are studied through simulations.